161 Btk inhibitors: friends or foes?

Phytoestrogens. Friends or foes?

BioInformatics Pipeline Alternative Splicing Services (BIPASS) offer support to scientists interested in gathering information related to alternative splicing (AS) events. The service BIPAS–SpliceDB provides access to AS information that has been extracted a priori from various public databases and stored in a data warehouse. In contrast, the BIPAS– Align&Splice service allows scientists to sub...

Proton pump inhibitors and Helicobacter pylori gastritis: friends or foes?

H. pylori gastritis and gastric acid closely interact. In H. pylori-positive patients, profound acid suppressive therapy induces a corpus-predominant pangastritis, which is associated with accelerated corpus gland loss and development of atrophic gastritis. Both corpus-predominant and atrophic gastritis have been associated with an increased risk of development of gastric cancer. H. pylori erad...

Beta-agonists--friends or foes?

Bacterial toxins: friends or foes?

Many emerging and reemerging bacterial pathogens synthesize toxins that serve as primary virulence factors. We highlight seven bacterial toxins produced by well-established or newly emergent pathogenic microbes. These toxins, which affect eukaryotic cells by a variety of means, include Staphylococcus aureus alpha-toxin, Shiga toxin, cytotoxic necrotizing factor type 1, Escherichia coli heat-sta...

Soybean Phytoestrogens – Friends or Foes?

Proper and balanced nutrition is very important in prevention and treatment of chronic diseases. Many individuals modify their diet and/or take different nutraceuticals expecting to attain optimum health, extend their lifespan and prevent diseases such as cardiovascular, cancer, osteoporosis, obesity, or diabetes type II. Based on „Japanese phenomenon“ (Adlercreutz, 1998), numerous advertisemen...